蓝舌病的研究。三株菌株在原代牛胎肾细胞培养中的研究。

Canadian journal of comparative medicine and veterinary science Pub Date : 1967-07-01

A Girard, G M Ruckerbauer, D P Gray, G L Bannister, P Boulanger

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引用次数: 0

摘要

三种不同的蓝舌病毒株适应于在原代牛胎肾细胞培养物中生长。从这三株菌株观察到的细胞病变效果是相似的，其特征是细胞收缩和粒度增加。荧光抗体技术证实了这种变化的特异性。血清病毒中和试验未发现明显的免疫交叉反应。

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Studies on bluetongue. IV. Studies of three strains in primary bovine foetal kidney cell cultures.

Three different strains of bluetongue virus were adapted to grow in primary bovine foetal kidney cell cultures. The cytopathic effects observed from the three strains were similar, and were characterized by shrinkage of cells and increased granularity. The specificity of the changes was confirmed by the fluorescent antibody technique. No significant immunological cross-reaction was detected by serum-virus neutralization tests from the strains studied.

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