{"title":"昆虫微粒体的生化特性:家蝇完整微粒体对NADPH的氧化","authors":"Margaret D Folsom, Ernest Hodgson","doi":"10.1016/0010-406X(70)90558-X","DOIUrl":null,"url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. The oxidation of reduced pyridine nucleotides by microsomal preparations from the abdomen of the adult housefly, <em>Musca domestica</em>, has been examined and characterized.</p></span></li><li><span>2.</span><span><p>2. NADPH oxidation is stimulated by exogenous cytochrome-<em>c</em> and inhibited by CO and sulfhydryl inhibitors.</p></span></li><li><span>3.</span><span><p>3. The effect of metal ions, synergists and known substrates for microsomal mixed function oxidases is also examined.</p></span></li><li><span>4.</span><span><p>4. Added xenobiotics substrates are not required for NADPH oxidation by these preparations.</p></span></li></ul></div>","PeriodicalId":78189,"journal":{"name":"Comparative biochemistry and physiology","volume":"37 3","pages":"Pages 301-310"},"PeriodicalIF":0.0000,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-406X(70)90558-X","citationCount":"21","resultStr":"{\"title\":\"Biochemical characteristics of insect microsomes: NADPH oxidation by intact microsomes from the housefly, Musca domestica\",\"authors\":\"Margaret D Folsom, Ernest Hodgson\",\"doi\":\"10.1016/0010-406X(70)90558-X\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p></p><ul><li><span>1.</span><span><p>1. The oxidation of reduced pyridine nucleotides by microsomal preparations from the abdomen of the adult housefly, <em>Musca domestica</em>, has been examined and characterized.</p></span></li><li><span>2.</span><span><p>2. NADPH oxidation is stimulated by exogenous cytochrome-<em>c</em> and inhibited by CO and sulfhydryl inhibitors.</p></span></li><li><span>3.</span><span><p>3. The effect of metal ions, synergists and known substrates for microsomal mixed function oxidases is also examined.</p></span></li><li><span>4.</span><span><p>4. Added xenobiotics substrates are not required for NADPH oxidation by these preparations.</p></span></li></ul></div>\",\"PeriodicalId\":78189,\"journal\":{\"name\":\"Comparative biochemistry and physiology\",\"volume\":\"37 3\",\"pages\":\"Pages 301-310\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1970-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0010-406X(70)90558-X\",\"citationCount\":\"21\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Comparative biochemistry and physiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0010406X7090558X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comparative biochemistry and physiology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0010406X7090558X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Biochemical characteristics of insect microsomes: NADPH oxidation by intact microsomes from the housefly, Musca domestica
1.
1. The oxidation of reduced pyridine nucleotides by microsomal preparations from the abdomen of the adult housefly, Musca domestica, has been examined and characterized.
2.
2. NADPH oxidation is stimulated by exogenous cytochrome-c and inhibited by CO and sulfhydryl inhibitors.
3.
3. The effect of metal ions, synergists and known substrates for microsomal mixed function oxidases is also examined.
4.
4. Added xenobiotics substrates are not required for NADPH oxidation by these preparations.
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