[脑和其他器官的氨基水解酶及其活性的调节]。

Voprosy biokhimii mozga Pub Date : 1974-01-01
A V Arutiunian
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引用次数: 0

摘要

讨论了通过脑和其他组织的amp -氨基水解酶水解腺苷酸脱氨的现有概念。讨论了组织中amp -氨基水解酶的含量、在细胞内的分布、理化性质、生理作用及其活性调控。将脑的amp -氨基水解酶与其他组织(肌肉、肝脏、肾脏、红细胞等)的amp -氨基水解酶进行比较,包括其在脑组织中活性调控的特征。在实验和现有资料的基础上,讨论了核苷酸、磷有机化合物、己糖激酶和某些阳离子参与脑和其他组织amp -氨基水解酶活性的调节。
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[AMP-aminohydrolase of the brain and other organs and the regulation of its activity].

Present concepts of the hydrolytic deamination of adenylic acid through AMP-aminohydrolase of brain and other tissues are discussed. The content of AMP-aminohydrolase of tissues, its intracellular disposition, physico-chemical properties, physiological role and the regulation of its activity are considered. AMP-aminohydrolase of brain is compared with that of other tissues (muscle, liver, kidney, erythrocytes, etc.), and characteristic features of the regulation of its activity in brain tissue is included. The participation of nucleotides, phosphoorganic compounds, hexokinase and some cations in the regulation of AMP-aminohydrolase activity of brain and other tissues are discussed on the basis of the experiments carried out and the data available.

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