[用药物干预血液沉积]。

Archivio di fisiologia Pub Date : 1973-12-01
P Zamboni, G Siro-Brigiani, G Renna
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引用次数: 0

摘要

这项研究的目的是看看某些药物是否能够将血液输送到老鼠的特定器官中。方法如下:将大鼠颈动脉与生理盐水血浆容器连接;动物被固定在一个有中心支点的平衡上;由于药物对动物的作用,通过天平的运动和进出容器的液体之间的关系,就有可能稳定血液流出的身体部位。0.25 -1杯/公斤剂量的异丙肾上腺素的主要作用是在肝脏中积累血液:这些血液从尾部流向这些器官。当剂量为3-30马克杯/公斤时,肠素的作用是使血液在肝脏和口腔中积聚。当剂量为1-4杯/公斤时,氨甲酰胆碱的作用是使血液在腹部积聚,部分在肝脏积聚;这些血液从头部流向腹部。
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[Interventions with drugs on blood deposits].

The aim of this study is to see if some drugs are able to lodge blood in specific organs, in the Rat. The metodic is the follow: the rat's carotid is connected to a container of saline plasma; the animal is fastened to a balance with central fulcrum; by the relation between the movements of the balance and the liquid entered and come out from the container, because of the action of the drugs on the animal, it is possible to stabilish the part of the body from which the blood is moved. The prevailing effect of 0,25-1 mug/kg doses of isoprenalin is an accumulation of blood in the liver: this blood comes from caudal parts to these organs. The enteramin's effect, for doses of 3-30 mug/kg, is an accumulation of blood in the liver and in the torax. The carbamylcholin's effect, for doses of 1-4 mug/kg, is an accumulation of blood in the abdomen and partially in the liver; this blood comes from cranial parts to the abdomen.

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[Effect of motor stimulation and stretching on afferent activity of the neuromuscular spindle isolated from the frog]. [Effects of acetylcholine and succinylcholine on isolated frog neuromuscular spindle]. The variation of characteristics of twitch and tetanic contractions with sarcomere length in isolated muscle fibres of the frog. [Current developments on the physiology of the cardiac atrial pacemaker an excitation conduction of the left atrium]. [Giulio Cesare Pupilli. Milan, 5 October 1893-Pescia, 17 August 1973].
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