[马提尼克岛献血者体内存在抗htlv(人类t细胞白血病病毒)抗体]。

G de Thé, M F McLane, N Monplaisir, T H Lee, M Essex
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引用次数: 0

摘要

利用间接膜免疫荧光法检测未固定的HUT 102细胞,从马提尼克岛定期献血者收集的184份血清中发现24份(13%)HTLV-MA抗体呈阳性,10份呈强阳性(5.4%)。其中6个血清在凝胶电泳中进一步进行放射免疫沉淀检测。其中5例检测到病毒主要核心蛋白(p24)和病毒特异性膜相关糖蛋白(gp 61)抗体。这些发现提出了马提尼克岛是否存在HTLV相关疾病(白血病或艾滋病)的问题。
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[Presence of anti-HTLV (human T-cell leukemia virus) antibodies in blood donors from Martinique].

Using indirect membrane immunofluorescence on unfixed HUT 102 cells, 24 out of 184 sera (13%) collected from regular blood donors in Martinique were found positive for HTLV-MA antibodies, 10 being strongly positive (5.4%). Six of these sera were further tested by radio-immunoprecipitation in gel electrophoresis. Antibodies to both viral main core protein (p24) and to virus specific membrane associated glycoprotein (gp 61) were detected in five of those. These findings raise the question of the existence of HTLV related conditions (leukemias or AIDS) in Martinique.

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