一种缓释茶碱:armophylline的多中心研究。

Le Poumon et le coeur Pub Date : 1983-01-01

G Akoun, J P Battesti, J Bignon, I Caubarrere, J Charpin, J F Chicou, P Godard, D M Herman, D Julien, F B Michel

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引用次数: 0

摘要

在一项涉及10个中心的合作研究中，95名哮喘患者接受了Armophylline(一种新的缓释茶碱)治疗，为期1至3个月。接受11 - 15mg /kg/天剂量药物治疗的患者中，80%的患者立即有足够的血茶碱水平(7- 20mcg /ml)。呼吸困难和哮喘发作次数显著减少，FEV1和FEV1/VC比值显著升高。这种药通常耐受性很好。副作用，如失眠、头痛或消化系统紊乱，通常是轻微的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Multicenter study of a slow-release theophylline: armophylline].

In a co-operative study involving 10 centres, 95 asthmatic patients were treated with Armophylline, a new slow-release theophylline for a period of 1 to 3 months. Eighty per cent of the patients receiving the drug in doses of 11 to 15 mg/kg/day immediately had adequate blood theophylline levels (7-20 mcg/ml). There was a significant decrease in dyspnoea and number of asthmatic attacks and a significant increase in FEV1 and FEV1/VC ratio. The drug was usually well tolerated. Side-effects, such as insomnia, headache or digestive disorders were, as a rule, mild.

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Le Poumon et le coeur

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