{"title":"应用微型计算机酶免疫分析法(Emit)测定血清奎尼丁浓度。","authors":"M S Sealfon, N Hallberg","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Quinidine is a commonly used drug for the treatment of cardiac arrhythmias. Avoidance of toxicity and monitoring of therapy can be readily accomplished by determining serum concentrations of quinidine by enzyme immunoassay (Emit) using a centrifugal analyzer and reducing the data with a desk-top microcomputer. For therapeutic and toxic drug ranges maximum within-run CV was under 6.0%, while between-run CV was under 10.0% in the therapeutic range and under 15.0% in the toxic range.</p>","PeriodicalId":76595,"journal":{"name":"The American journal of medical technology","volume":"49 9","pages":"669-70"},"PeriodicalIF":0.0000,"publicationDate":"1983-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The application of a microcomputer for enzyme immunoassay (Emit) determination of serum quinidine concentrations.\",\"authors\":\"M S Sealfon, N Hallberg\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Quinidine is a commonly used drug for the treatment of cardiac arrhythmias. Avoidance of toxicity and monitoring of therapy can be readily accomplished by determining serum concentrations of quinidine by enzyme immunoassay (Emit) using a centrifugal analyzer and reducing the data with a desk-top microcomputer. For therapeutic and toxic drug ranges maximum within-run CV was under 6.0%, while between-run CV was under 10.0% in the therapeutic range and under 15.0% in the toxic range.</p>\",\"PeriodicalId\":76595,\"journal\":{\"name\":\"The American journal of medical technology\",\"volume\":\"49 9\",\"pages\":\"669-70\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1983-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The American journal of medical technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The American journal of medical technology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The application of a microcomputer for enzyme immunoassay (Emit) determination of serum quinidine concentrations.
Quinidine is a commonly used drug for the treatment of cardiac arrhythmias. Avoidance of toxicity and monitoring of therapy can be readily accomplished by determining serum concentrations of quinidine by enzyme immunoassay (Emit) using a centrifugal analyzer and reducing the data with a desk-top microcomputer. For therapeutic and toxic drug ranges maximum within-run CV was under 6.0%, while between-run CV was under 10.0% in the therapeutic range and under 15.0% in the toxic range.
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