绵羊中主要的OLA组织相容性复合体。6个新因子的研究和复合体第三位点的定义:OLA-C。

P Millot
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引用次数: 0

摘要

本文描述了绵羊组织相容性复合体的6个新的OLA因子。其中,c14、c15、c17是该复合体的第三个位点OLA-C上3个等位基因的产物,与OLA-A和B紧密相连。两个因子a13和b12是OLA-A和B上2个等位基因的产物。最后一个因子(16)是一个OLA基因的产物,其位点尚未确定。共有28个单倍型。3个OLA位点的基因处于连锁不平衡状态。
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[The major OLA histocompatibility complex in sheep. Study of 6 new factors and definition of a 3rd locus of the complex: OLA-C].

6 new OLA factors of the Sheep histocompatibility complex are described. 3 of them, C 14, C 15, C 17 are the products of 3 alleles at a third locus of the complex: OLA-C, closely linked to OLA-A and B. Two factors A 13 and B 12 are the products of 2 alleles at OLA-A and B loci. The last factor (16) is the product of an OLA gene, the locus of which is not yet defined. 28 haplotypes are described. Genes at the 3 OLA loci are in linkage disequilibrium.

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