O Kobori, J Watanabe, T Shimizu, M Shoji, Y Morioka
{"title":"牛磺胆酸钠对n -甲基-n '-硝基-n -亚硝基胍诱导大鼠胃肿瘤发生的促进作用。","authors":"O Kobori, J Watanabe, T Shimizu, M Shoji, Y Morioka","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Male Wistar rats that had received a low dose of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and sodium taurocholate showed a significantly higher incidence of hyperplastic and neoplastic lesions in the stomach mucosa than did the MNNG-treated controls. The result suggested an enhancing effect of taurocholate in stomach tumorigenesis.</p>","PeriodicalId":12660,"journal":{"name":"Gan","volume":"75 8","pages":"651-4"},"PeriodicalIF":0.0000,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Enhancing effect of sodium taurocholate on N-methyl-N'-nitro-N-nitrosoguanidine-induced stomach tumorigenesis in rats.\",\"authors\":\"O Kobori, J Watanabe, T Shimizu, M Shoji, Y Morioka\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Male Wistar rats that had received a low dose of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and sodium taurocholate showed a significantly higher incidence of hyperplastic and neoplastic lesions in the stomach mucosa than did the MNNG-treated controls. The result suggested an enhancing effect of taurocholate in stomach tumorigenesis.</p>\",\"PeriodicalId\":12660,\"journal\":{\"name\":\"Gan\",\"volume\":\"75 8\",\"pages\":\"651-4\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1984-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gan\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gan","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Enhancing effect of sodium taurocholate on N-methyl-N'-nitro-N-nitrosoguanidine-induced stomach tumorigenesis in rats.
Male Wistar rats that had received a low dose of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and sodium taurocholate showed a significantly higher incidence of hyperplastic and neoplastic lesions in the stomach mucosa than did the MNNG-treated controls. The result suggested an enhancing effect of taurocholate in stomach tumorigenesis.
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