用雌激素刺激未成熟兔子的子宫内膜,并用孕激素治疗。扫描电镜研究]。

J Paris, E Mrena, A Lanquetin, G M Marchal, R Thevenot
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引用次数: 0

摘要

采用常规药理学方法对兔子宫内膜进行假孕酮作用的扫描电镜观察。雌激素刺激后,纤毛细胞数量倍增。黄体酮治疗导致微绒毛数量减少,出现圆形凸起,其数量随着黄体酮剂量的增加而增加。这些变化与绝经后接受雌激素-孕激素治疗的妇女观察到的变化非常接近。
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[The endometrium of the immature rabbit stimulated by an estrogen and treated with a progestogen. Scanning electron microscopy study].

The endometrium of rabbits, treated by the usual pharmacology methods designed for the measurement of the pseudogestagen effect, was studied by scanning electron microscopy. Estrogen stimulation was followed by a multiplication of the number of ciliated cells. Treatment with progesterone lead to a decrease in the numbers of microvilli and to the appearance of rounded bulges which increased in numbers as the progesterone dose level increased. These changes were quite close to those observed in post menopausal women under estro-progestogen treatment.

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