J A D'Elia, A Kaldany, D G Miller, A Rolla, L A Weinrauch
{"title":"消除外源性胰岛素治疗对糖尿病性肾衰竭的需求。","authors":"J A D'Elia, A Kaldany, D G Miller, A Rolla, L A Weinrauch","doi":"10.3109/08860228209050815","DOIUrl":null,"url":null,"abstract":"<p><p>Four insulin-dependent diabetics became insulin-independent sometime after beginning maintenance dialysis for renal failure. Spontaneous hypoglycemia occurred after insulin was discontinued in two individuals treated with peritoneal dialysis. Although weight loss was significant in each, three of the four maintained ideal body weight. By diminishing the insulin resistance of uremia, dialysis may play an active role in promoting the metabolic effect of endogenous insulin even in diabetics with multiple complications of hyperglycemia.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228209050815","citationCount":"6","resultStr":"{\"title\":\"Elimination of requirement for exogenous insulin therapy in diabetic renal failure.\",\"authors\":\"J A D'Elia, A Kaldany, D G Miller, A Rolla, L A Weinrauch\",\"doi\":\"10.3109/08860228209050815\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Four insulin-dependent diabetics became insulin-independent sometime after beginning maintenance dialysis for renal failure. Spontaneous hypoglycemia occurred after insulin was discontinued in two individuals treated with peritoneal dialysis. Although weight loss was significant in each, three of the four maintained ideal body weight. By diminishing the insulin resistance of uremia, dialysis may play an active role in promoting the metabolic effect of endogenous insulin even in diabetics with multiple complications of hyperglycemia.</p>\",\"PeriodicalId\":79208,\"journal\":{\"name\":\"Clinical and experimental dialysis and apheresis\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1982-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3109/08860228209050815\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical and experimental dialysis and apheresis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3109/08860228209050815\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and experimental dialysis and apheresis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/08860228209050815","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Elimination of requirement for exogenous insulin therapy in diabetic renal failure.
Four insulin-dependent diabetics became insulin-independent sometime after beginning maintenance dialysis for renal failure. Spontaneous hypoglycemia occurred after insulin was discontinued in two individuals treated with peritoneal dialysis. Although weight loss was significant in each, three of the four maintained ideal body weight. By diminishing the insulin resistance of uremia, dialysis may play an active role in promoting the metabolic effect of endogenous insulin even in diabetics with multiple complications of hyperglycemia.