X Ronot, D Kuch, C Hecquet, M Adolphe, P Lechat, G Deysson
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引用次数: 0
摘要
证实并分析了铃草对HeLa细胞动力学的抑制作用。循环细胞的百分比根据浓度下降，在7.5 ~ 2.5 × 10(-5) m之间，通过细胞流式细胞光度法估计DNA显示循环细胞的分布发生了重要的变化，G1细胞相对减少，G2细胞非常重要地积累。根据我们的实验条件，只有在7.5 x 10(-5) M时，G2中的堵塞才不可逆。
[Inhibitory effect of cytembena (sodium-cis-beta-methoxybenzoyl-beta-bromoacrylate) on the cell kinetics of HeLa cells in culture].
The inhibiting effect of Cytembena on HeLa cell kinetics has been demonstrated and analyzed. The percentage of cycling cells decreases, according to the concentration, between 7.5 and 2.5 x 10(-5) M. Estimation of DNA by cell flow cytophotometry shows an important shift in the distribution of cycling cells with a relative decrease of G1 cells and a very important accumulation of G2 cells. According to our experimental conditions, the blocking up in G2 is irreversible only at 7.5 x 10(-5) M.
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