C Abe, J Y Homma, H Noda, R Yanagawa, K Morihara, H Tsuzuki, S Takeuchi
{"title":"多组分疫苗与福尔马林灭活细胞疫苗对水貂铜绿假单胞菌出血性肺炎地方性流行的防护效果比较。","authors":"C Abe, J Y Homma, H Noda, R Yanagawa, K Morihara, H Tsuzuki, S Takeuchi","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Effectiveness of a multi-component vaccine consisting of the common antigen (OEP) derived from Pseudomonas aeruginosa strain N 10 (serotype E) and toxoids of protease and elastase was compared with that of formalin-killed cells of strain N 10 on protection against enzootic of hemorrhagic pneumonia due to P. aeruginosa in mink. One administration of the multi-component vaccine (100 microgram each of OEP, protease toxoid and elastase toxoid) clearly prevented enzootic of hemorrhagic pneumonia due to P. aeruginosa (serotype G) in mink, while a vaccination of formalin-killed cells was much less effective in preventing an epidemic. The difference in mortality rates between two vaccines was remarkable.</p>","PeriodicalId":23929,"journal":{"name":"Zentralblatt fur Bakteriologie. 1. Abt. Originale. A: Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"249 3","pages":"413-7"},"PeriodicalIF":0.0000,"publicationDate":"1981-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of the effects of a multi-component vaccine and a formalin-killed cell vaccine on protection against enzootic of hemorrhagic pneumonia due to Pseudomonas aeruginosa in mink.\",\"authors\":\"C Abe, J Y Homma, H Noda, R Yanagawa, K Morihara, H Tsuzuki, S Takeuchi\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Effectiveness of a multi-component vaccine consisting of the common antigen (OEP) derived from Pseudomonas aeruginosa strain N 10 (serotype E) and toxoids of protease and elastase was compared with that of formalin-killed cells of strain N 10 on protection against enzootic of hemorrhagic pneumonia due to P. aeruginosa in mink. One administration of the multi-component vaccine (100 microgram each of OEP, protease toxoid and elastase toxoid) clearly prevented enzootic of hemorrhagic pneumonia due to P. aeruginosa (serotype G) in mink, while a vaccination of formalin-killed cells was much less effective in preventing an epidemic. The difference in mortality rates between two vaccines was remarkable.</p>\",\"PeriodicalId\":23929,\"journal\":{\"name\":\"Zentralblatt fur Bakteriologie. 1. Abt. Originale. A: Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie\",\"volume\":\"249 3\",\"pages\":\"413-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1981-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zentralblatt fur Bakteriologie. 1. Abt. Originale. A: Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zentralblatt fur Bakteriologie. 1. Abt. Originale. A: Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Comparison of the effects of a multi-component vaccine and a formalin-killed cell vaccine on protection against enzootic of hemorrhagic pneumonia due to Pseudomonas aeruginosa in mink.
Effectiveness of a multi-component vaccine consisting of the common antigen (OEP) derived from Pseudomonas aeruginosa strain N 10 (serotype E) and toxoids of protease and elastase was compared with that of formalin-killed cells of strain N 10 on protection against enzootic of hemorrhagic pneumonia due to P. aeruginosa in mink. One administration of the multi-component vaccine (100 microgram each of OEP, protease toxoid and elastase toxoid) clearly prevented enzootic of hemorrhagic pneumonia due to P. aeruginosa (serotype G) in mink, while a vaccination of formalin-killed cells was much less effective in preventing an epidemic. The difference in mortality rates between two vaccines was remarkable.
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