L Lebrun, C Tram, F Lapierre, L Grangeot-Keros, J Pillot
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Detection of Legionella pneumophila antigen by ELISA in urine or experimentally infected guinea-pigs.
Guinea-pigs were experimentally infected with Legionella pneumophila. L. pneumophila antigen was detected in urine samples by a double antibody sandwich ELISA. Urinary antigen was present from the beginning of the acute phase of the disease. In two out of five cases, this antigen was found with no antibody detectable in sera by indirect immunofluorescence staining.
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