高危高血压妊娠:孕产妇和胎儿结局。

J S Horvath, A Phippard, D H Smart, A Korda, G G Duggin, B M Hall, D J Tiller
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引用次数: 2

摘要

236名孕妇接受了高血压和/或肾脏疾病的评估和治疗。一个由一名医生、一名产科医生和一名围产期医生组成的小组对每位病人进行联合评估,并就治疗提供建议。所有患者均住院并卧床休息。药物治疗为盐酸可乐定或甲基多巴,部分患者加用血管扩张剂。分娩的决定取决于胎儿的成熟度和健康状况,以及母亲的状况。无产妇死亡,总围产期生存率为97%。这些妊娠的结果与先前报道的研究结果比较有利,反映了一种成功的方法来管理高危高血压妊娠。
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High risk hypertensive pregnancies: maternal and foetal outcome.

Two hundred and thirty-six pregnant women were referred for assessment and management of hypertension and/or renal disease. A Unit consisting of a physician, an obstetrician and a perinatologist jointly assessed each patient and advised on management. All patients were hospitalized and at bed rest. Drug therapy was clonidine hydrochloride or methyl dopa and in some patients a vasodilator was added. The decision to deliver was dictated by foetal maturity and wellbeing, in conjunction with maternal condition. There was no maternal mortality and the overall perinatal survival was 97%. The outcome of these pregnancies compares favourably with studies previously reported and reflect a successful approach to management of high risk hypertensive pregnancies.

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Pre-eclampsia in a second pregnancy. A clinical follow-up study of 260 women with hypertension in pregnancy. Beta blocker therapy in 125 cases of hypertension during pregnancy. Disposition of the adrenergic blocker metoprolol in the late pregnant women, the amniotic fluid, the cord blood and the neonate. Maternal-fetal immunity: presence of specific cellular hyporesponsiveness and humoral suppressor activity in normal pregnancy and their absence in preeclampsia.
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