[继发性感染的肺膨出,嗜酸性粒细胞增多和IgE的过量产生表现为成人巴克利综合征]。

Le Poumon et le coeur Pub Date : 1983-01-01
A B Tonnel, M Joseph, B Gosselin, P Gosset, E Fournier
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引用次数: 0

摘要

高IgE综合征发生于儿童期,可导致反复感染,通常为金黄色葡萄球菌,主要影响皮肤和肺实质。它可能与一个主要的面部非典型皮炎和更罕见的过敏表现有关。生物学试验主要显示嗜酸性粒细胞增多症和高γ球蛋白血症E,其他免疫球蛋白类型无改变。中性粒细胞和单核细胞趋化性障碍是不稳定的表现。这种影响的最初机制似乎与选择性作用于IgE同型的抑制性T功能缺陷有关。
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[Secondarily infected pneumatocele, eosinophilia and excess production of IgE manifesting as Buckley's syndrome in an adult].

The hyper IgE syndrome develops in childhood and leads to repeated infectious episodes, usually of staphylococcus aureus origin and affecting mainly the skin and pulmonary parenchyma. It may be associated with a predominantly facial atypical dermatitis and more rarely with allergic manifestations. Biological tests show mainly an eosinophilia and a hypergammaglobulinemia E alone without modifications in other immunoglobulin types. Disorders of neutrophil and monocyte chemotaxis are inconstant findings. The initial mechanism of the affection appears related to a deficit in suppressive T function selectively acting on the IgE isotype.

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[Drug-induced respiratory disorders]. [Effector functions of the polynuclear eosinophil]. [Small cell epithelioma in the Rhône-Alp region: changes in incidence between 1970 and 1980]. [Granular cell bronchial tumors. General features, developmental and therapeutic aspects. Apropos of 4 new cases]. [A rare tumor: benign sclerosing pneumocytoma with an intrascissural development].
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