大鼠T淋巴细胞和骨髓细胞上的螺旋鱼受体。

J A Killen, J H Holda, R H Swanborg
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引用次数: 1

摘要

螺旋果状体(HP)受体存在于大约60%的神经氨酸酶(NANAase)处理的大鼠T淋巴细胞上。HP+脾细胞(SpC)可以通过亲和层析法从HP-、免疫球蛋白(Ig+)细胞中分离出来。HP+ SpC介导局部移植物抗宿主反应(GVHR)。不到1%的大鼠淋巴细胞同时携带HP和Ig标记物。大约25%的Lewis大鼠骨髓细胞为HP+(仅1%为HP+ Ig+),提示HP受体可能是一种分化标志物。
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Helix pomatia receptors on rat T lymphocytes and bone marrow cells.

Helix pomatia (HP) receptors are present on approximately 60 percent of neuraminidase (NANAase)-treated rat T lymphocytes. The HP+ spleen cells (SpC) can be separated from HP-, immunoglobulin-bearing (Ig+) cells by affinity chromatography. The HP+ SpC mediate the local graft-versus-host reaction (GVHR). Less than 1% of rat lymphocytes bear both HP and Ig markers. Approximately 25% of Lewis rat bone marrow cells are HP+ (only 1% are HP+ Ig+), suggesting that the HP receptor may be a differentiation marker.

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