肥胖与动脉高血压的关系

La Nouvelle presse medicale Pub Date : 1982-12-04
F Cambien
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引用次数: 0

摘要

肥胖和原发性高血压之间的统计学相关性已经得到证实。体重减轻对血压的有益影响和体重增加对血压的有害影响也已被反复证明。这种相关性背后的病理生理机制尚不清楚,但人们提出了各种各样的假设,这些假设有时有利于不同类型的饮食。一些研究表明,能量限制和盐限制可能有独立的有益效果。此外,与肥胖相关的代谢异常通常通过饮食得到改善,而降压药可能具有有害作用。了解血压对饮食的反应是否取决于肥胖的类型,将是一项有趣的研究。对照临床试验比较药物和饮食的效果是非常可取的。
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[Relationship between obesity and arterial hypertension].

The statistical correlation between obesity and essential hypertension is well established. The beneficial effect of weight reduction and the detrimental effect of weight gain on blood pressure have also been repeatedly demonstrated. The pathophysiological mechanisms underlying this correlation are still obscure, but various hypotheses, which sometimes favour different types of diet, have been put forward. Some studies suggest that energy restriction and salt restriction might have independent beneficial effects. Furthermore, the metabolic abnormalities associated with obesity are often improved by diet, whereas antihypertensive drugs may have deleterious effects. It would be of interest to know whether blood pressure response to diet is dependent upon the type of obesity. Controlled clinical trials comparing the effects of drugs and diet are highly desirable.

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