脑室注射胆囊收缩素抗血清对大鼠主动回避和条件进食行为的影响。

M Fekete, M Balázs, G Telegdy
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引用次数: 0

摘要

研究了两种不同胆囊收缩素抗血清对大鼠主动回避行为的获得和消退以及条件摄食行为的获得、维持和消退的影响。两种抗血清均延迟了主动回避和条件进食反应的消退,但在获取和维持方面无效。这些数据表明,大脑的内源性CCK可能是消退过程的生理调节剂。
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Effects of intracerebroventricularly administered cholecystokinin antisera on active avoidance and conditioned feeding behaviour of rats.

The effects of intracerebroventricular administration of two different cholecystokinin antisera were tested on acquisition and extinction of active avoidance behaviour as well as on acquisition, maintenance and extinction of conditioned feeding behaviour of rats. Both antisera delayed the extinction of active avoidance and conditioned feeding response, while they were ineffective on acquisition and maintenance. These data suggest that the endogenous CCK of the brain might be a physiological modulator of extinction processes.

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