{"title":"母体血液抗m血清学研究致新生儿溶血病1例。","authors":"H Matsumoto, Y Tamaki, S Sato, K Shibata","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>These case is described of a woman with repeated stillbirths. Her serum contained high-titered anti-M antibodies. Treatment of the serum with 2-mercaptoethanol resulted in do reduction in anti-M titer. The serum fraction consisting mainly of IgG exhibited a markedly high anti-M titer compared with the IgM fraction. Anti-M antibodies eluted from OM red cells could be removed by precipitation with specific anti-IgG. Thus, the repeated stillbirths are ascribed to IgG and anti-M antibodies were formed during incompatible pregnancy and crossed the placenta.</p>","PeriodicalId":75398,"journal":{"name":"Acta obstetrica et gynaecologica Japonica","volume":"33 4","pages":"525-8"},"PeriodicalIF":0.0000,"publicationDate":"1981-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A case of hemolytic disease of the newborn caused by anti-M: serological study of maternal blood.\",\"authors\":\"H Matsumoto, Y Tamaki, S Sato, K Shibata\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>These case is described of a woman with repeated stillbirths. Her serum contained high-titered anti-M antibodies. Treatment of the serum with 2-mercaptoethanol resulted in do reduction in anti-M titer. The serum fraction consisting mainly of IgG exhibited a markedly high anti-M titer compared with the IgM fraction. Anti-M antibodies eluted from OM red cells could be removed by precipitation with specific anti-IgG. Thus, the repeated stillbirths are ascribed to IgG and anti-M antibodies were formed during incompatible pregnancy and crossed the placenta.</p>\",\"PeriodicalId\":75398,\"journal\":{\"name\":\"Acta obstetrica et gynaecologica Japonica\",\"volume\":\"33 4\",\"pages\":\"525-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1981-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta obstetrica et gynaecologica Japonica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta obstetrica et gynaecologica Japonica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A case of hemolytic disease of the newborn caused by anti-M: serological study of maternal blood.
These case is described of a woman with repeated stillbirths. Her serum contained high-titered anti-M antibodies. Treatment of the serum with 2-mercaptoethanol resulted in do reduction in anti-M titer. The serum fraction consisting mainly of IgG exhibited a markedly high anti-M titer compared with the IgM fraction. Anti-M antibodies eluted from OM red cells could be removed by precipitation with specific anti-IgG. Thus, the repeated stillbirths are ascribed to IgG and anti-M antibodies were formed during incompatible pregnancy and crossed the placenta.