[给药胸腺激素对Jensen肉瘤大鼠胸腺因子水平的改变及肿瘤生长速率的影响]。

E Busse, H Rose
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引用次数: 0

摘要

对詹森肉瘤细胞移植后的大鼠进行不同的处理,检测Doparkin (cAMP水平升高)、morbilli疫苗(干扰素诱诱剂)和局部放疗单独或联合对肿瘤生长速率的影响。将这些药物与局部放射治疗相结合,肿瘤生长率最低。胸腺因子水平的分析显示,与正常动物相比,肿瘤动物的胸腺因子水平显著降低,而与没有肿瘤形成的动物相比,治疗的结果是。分别单独应用胸腺因子与多帕金疫苗和莫比利疫苗联合使用可明显降低肿瘤的生长率。
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[Changes in the thymic factor level in rats with Jensen sarcoma and modification of the rate of tumor growth by administration of thymic hormone].

Rats were differently treated after transplantation of cells of Jensen sarcoma to test the influence of Doparkin (increase of the cAMP level), morbilli vaccine (interferon inductor) and local radio-therapy alone or in combination for a decrease of the rate of growing tumors. The lowest rate of growing tumors was received by combining the agents with a local radio-therapy. The analysis of the thymic factor level showed in the animals with a tumor a significant reduction in comparison to normal animals respectively to animals without tumor formation in consequence of the therapy. An application of the thymic factor alone respectively in combination with Doparkin and morbilli vaccine leads to a clear decrease of the rate of growing tumors.

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