[乙型肝炎病毒从携带乙肝表面抗原的妇女传染给丈夫的可能性研究[作者译]。

H Aoki, N Inaba, R Ohkawa, J Kudoh, H Takamizawa
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引用次数: 0

摘要

为评估乙型肝炎病毒(HBV)可能的性传播,对乙肝表面抗原(HBsAg)携带者的丈夫进行了婚后急性肝炎的发生率调查以及乙肝表面抗原(HBsAg)和抗体(HBsAb)的流行情况。探讨了乙肝病毒携带者妻子对丈夫HBV感染的可能感染途径及影响因素。本研究证明:1。在接受检查的丈夫中,发现HBV暴露标记为32.8%,而婚后肝炎的发生率高达7.2%。乙肝病毒从携带乙肝表面抗原的妇女传染给她们的丈夫应该发生在婚后不久。HBsAg携带者血清E-Ag和e-Ab可分别作为HBV传播阳性和阴性的指标。在R-PHA血清hbsag滴度高于39的妻子中,观察到HBV高暴露标记(87.5%)。3.对HBsAg携带者不同体液HBsAg检出率和滴度的检测结果提示,宫颈黏液和阴道分泌物可能在HBV性传播中起重要作用。
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[A study on the possible transmission of hepatitis B virus from HBsAg carrier women to their husbands (author's transl)].

In order to assess the possible sexual transmission of hepatitis B virus (HBV), the occurrence of post-marital acute hepatitis and the prevalence of hepatitis B surface antigen (HBsAg) and antibody (HBsAb) were investigated among the husbands of HBsAg carrier women. The possible infectious routes and influencing factors in the HBV infection of the husbands by their HBsAg carrier wives were also discussed. This study demonstrates: 1. In the husbands examined, the exposure marker of HBV was found to be 32.8 per cent and the occurrence rate of post-marital hepatitis came up to 7.2 per cent. 2. The transmission of HBV from HBsAg carrier women to their husbands was supposed to take place shortly after marriage. E-Ag and e-Ab in ther sera of HBsAg carrier women could serve respectively as indicators of positive and negative HBV transmission. In the husbands with wives whose serum HBsAg-titers by R-PHA were higher than 39, a high exposure marker of HBV (87.5%) was observed. 3. The results of HBsAg detection rates and titers in various kinds of body fluids obtained from HBsAg carrier women suggested that cervical mucus and vaginal discharge might play an important role in the sexual HBV transmission.

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