胆囊收缩素抗血清对大鼠脑单胺含量的影响。

M Fekete, T Kádár, G Telegdy
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引用次数: 0

摘要

研究了三种稀释度的CCK抗血清对大鼠下丘脑、杏仁核、中隔、纹状体和大脑皮层多巴胺(DA)、去甲肾上腺素(NE)和5-羟色胺(5-HT)含量的影响。CCK抗血清降低了下丘脑、中脑、杏仁核和中隔DA和NE含量,提高了纹状体DA含量,降低了NE含量。对大鼠杏仁核、中隔和纹状体的5-HT含量有轻微影响。
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Effect of cholecystokinin antiserum on the brain monoamine content in rats.

The effects of intracerebroventricular administration of cholecystokinin (CCK) antiserum )specific for COOH-terminal four amino acids) of CCK were tested in three dilutions on the dopamine (DA), norepinephrine (NE) and serotonin (5-HT) contents of the hypothalamus, amygdala, septum, striatum and cerebral cortex in rats 24 h following application. CCK antiserum decreased the DA and NE contents in the hypothalamus, mesencephalon, amygdala and septum, while it increased the DA content and decreased the NE content of the striatum. It had a slight effect on the 5-HT contents of the amygdala, septum and striatum.

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