先天性巨结肠术后乙酰胆碱酯酶活性。

S Goto, K Ikeda, K Kume, A Nakagawara
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引用次数: 3

摘要

采用z型吻合术治疗巨结肠病患者的直肠吸活检组织进行组织化学染色和乙酰胆碱酯酶(AChE)活性生化测定。术后直肠前壁AChE活性及AChE/总AChE (% AChE)显著高于直肠后壁(p < 0.001)。生化AChE活性与视觉粘膜AChE活性相关性较好。值得注意的是,z型吻合后直肠前壁AChE活性长期保持在较高水平,与术后时间间隔、肛肠功能、直肛反射无关。
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Postoperative acetylcholinesterase activity in Hirschsprung's disease.

Histochemical staining and biochemical assay of acetylcholinesterase (AChE) activity were applied to rectal suction biopsy tissue from patients treated by Z-shaped anastomosis for Hirschsprung's disease. Postoperative AChE activity and AChE/Total ChE (% AChE) in the rectal anterior wall were significantly higher (p < 0.001) than those in the posterior wall. Biochemical AChE activity was well correlative to visual mucosal AChE activity. It is remarkable that AChE activity in the rectal anterior wall after Z-shaped anastomosis was found to be kept at high level for a long period without any relation to the time interval after the operation, the ano-rectal function, and the recto-anal reflex.

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