腺苷对大鼠心房对肾上腺素能刺激的变时反应的影响。

Archives internationales de physiologie, de biochimie et de biophysique Pub Date : 1993-11-01 DOI:10.3109/13813459309046987

O A Gende

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引用次数: 0

摘要

在腺苷存在的情况下，大鼠心房对β肾上腺素能刺激的变时反应需要更高浓度的激动剂。这种抗肾上腺素能作用可减轻心脏缺血时交感神经张力升高引起的心动过速。腺苷存在时，对α肾上腺素能刺激的敏感性没有改变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Effects of adenosine on chronotropic responses of rat atria to alpha and beta adrenergic stimulation.

The chronotropic response of rat atria to beta adrenergic stimulation required higher concentrations of agonist in the presence of adenosine. This anti beta-adrenergic effect could attenuate the tachycardia induced by the increased sympathetic tone during cardiac ischemia. The sensitivity to alpha adrenergic stimulation did not change in the presence of adenosine.

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Archives internationales de physiologie, de biochimie et de biophysique

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