小肠肿瘤。

Current opinion in general surgery Pub Date : 1993-01-01
M D Basson
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引用次数: 0

摘要

小肠肿瘤包括腺癌、类癌、淋巴瘤和肉瘤,以及各种良性息肉,应切除以排除恶性肿瘤。虽然传统上小肠肿瘤很难诊断,但提高怀疑指数应与改进的诊断技术相结合,以提高诊断率并减少诊断延误。在过去的一年中,生物活性类癌的治疗进展迅速。越来越多的稳定生长抑素类似物奥曲肽的使用经验使得这些肿瘤在慢性和急性“类癌危象”期间能够调节激素分泌。此外,利用该化合物的同位素标记变体可以促进早期鉴定。尽管先进的药物治疗探针的发展改善了对分泌性小肠肿瘤的治疗,但腺癌、淋巴瘤和肉瘤的预后仍然主要反映在诊断的延迟时间上,并等待对这些恶性病变病理生物学的进一步了解。
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Small bowel tumors.

Small bowel tumors include adenocarcinomas, carcinoids, lymphomas, and sarcomas, as well as a variety of benign polyps, which should be excised to rule out malignancy. Although small bowel tumors are traditionally difficult to diagnose, a heightened index of suspicion should be combined with improved diagnostic techniques to increase yield and decrease delays in identification. The management of bioactive carcinoid tumors has rapidly advanced over the past year. Increasing experience with the stable somatostatin analogue octreotide has enabled regulation of hormonal secretion by these tumors both chronically and during acute "carcinoid crisis." In addition, early identification may be facilitated by the use of isotopically labeled variants of the compound. Although the development of sophisticated pharmacotherapeutic probes has improved the management of secretory small intestinal tumors, the prognosis for adenocarcinomas, lymphomas, and sarcomas still primarily reflects on the time of delay in diagnosis and awaits an improved understanding of the pathobiology of these malignant lesions.

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