绝经期激素替代疗法的治疗前管理和监测。

P Bernard, M Galli, J Mollard
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引用次数: 0

摘要

绝经期激素替代疗法(HRT)的治疗前评估除了标准的妇科评估外,还需要某些措施。重要的是要确定任何可能的乳房或子宫内膜疾病,可能需要特定的治疗或调整标准的激素替代疗法。骨骼状态通过病史评估,必要时通过双光子吸收测定法。经过这样的评估,由于使用天然雌二醇和非雄激素孕激素,绝对禁忌症的数量很少。它们主要与乳腺癌和血栓栓塞史有关。第一次随访,在三个月时,可以确认治疗的可接受性和有效性,并在需要时进行调整。然后建议使用监视日历。
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[Pre-therapeutic management and surveillance of menopausal hormone replacement therapy].

Pre-therapeutic evaluation of menopausal hormone replacement therapy (HRT) requires certain measures in addition to a standard gynecological assessment. It is important to identify any possible breast or endometrial disorder which might require specific treatment or an adjustment of standard HRT. Skeletal status is assessed by history and, if necessary, by double-photon absorptiometry. Following such evaluation, absolute contra-indications are few in number, by virtue of the use of natural estradiol and non-androgenic progestogens. They essentially concern breast cancer and a thrombo-embolic history. The first follow-up visit, at three months, enables confirmation of the acceptability and efficacy of treatment and its adjustment if required. A monitoring calendar is then suggested.

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