心磷脂抗体在系统性红斑狼疮中的意义

Immunitat und Infektion Pub Date : 1995-02-01

S Gansauge, A Breitbart, B Brado, H von Baum, N Rinaldi, E Werle, M Schwarz-Eywill

{"title":"心磷脂抗体在系统性红斑狼疮中的意义","authors":"S Gansauge, A Breitbart, B Brado, H von Baum, N Rinaldi, E Werle, M Schwarz-Eywill","doi":"","DOIUrl":null,"url":null,"abstract":"The aim of the study was to investigate the frequency and clinical significance of anticardiolipin antibodies (aCL) in systemic lupus erythematosus (SLE). 32 of 100 patients with SLE had positive anticardiolipin antibodies. Increased aCL were associated with thrombosis, thrombocytopenia, miscarriage, vasculitic skin changes and neurological symptoms. The incidence of thrombosis, thrombocytopenia, and neurological symptoms was significantly increased in the aCL-positive group as compared to the aCL-negative group. These findings confirm the results of former investigations and underline the role of aCL in systemic lupus erythematosus.","PeriodicalId":75925,"journal":{"name":"Immunitat und Infektion","volume":"23 1","pages":"27-8"},"PeriodicalIF":0.0000,"publicationDate":"1995-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The significance of cardiolipin antibodies in systemic lupus erythematosus].\",\"authors\":\"S Gansauge, A Breitbart, B Brado, H von Baum, N Rinaldi, E Werle, M Schwarz-Eywill\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The aim of the study was to investigate the frequency and clinical significance of anticardiolipin antibodies (aCL) in systemic lupus erythematosus (SLE). 32 of 100 patients with SLE had positive anticardiolipin antibodies. Increased aCL were associated with thrombosis, thrombocytopenia, miscarriage, vasculitic skin changes and neurological symptoms. The incidence of thrombosis, thrombocytopenia, and neurological symptoms was significantly increased in the aCL-positive group as compared to the aCL-negative group. These findings confirm the results of former investigations and underline the role of aCL in systemic lupus erythematosus.\",\"PeriodicalId\":75925,\"journal\":{\"name\":\"Immunitat und Infektion\",\"volume\":\"23 1\",\"pages\":\"27-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1995-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Immunitat und Infektion\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Immunitat und Infektion","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

本研究的目的是探讨抗心磷脂抗体(aCL)在系统性红斑狼疮(SLE)中的频率和临床意义。100例SLE患者中有32例抗心磷脂抗体阳性。aCL升高与血栓形成、血小板减少、流产、血管性皮肤改变和神经系统症状有关。与acl阴性组相比，acl阳性组血栓形成、血小板减少和神经系统症状的发生率显著增加。这些发现证实了以前的调查结果，并强调了前交叉韧带在系统性红斑狼疮中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

微信好友朋友圈 QQ好友复制链接

本刊更多论文

[The significance of cardiolipin antibodies in systemic lupus erythematosus].

The aim of the study was to investigate the frequency and clinical significance of anticardiolipin antibodies (aCL) in systemic lupus erythematosus (SLE). 32 of 100 patients with SLE had positive anticardiolipin antibodies. Increased aCL were associated with thrombosis, thrombocytopenia, miscarriage, vasculitic skin changes and neurological symptoms. The incidence of thrombosis, thrombocytopenia, and neurological symptoms was significantly increased in the aCL-positive group as compared to the aCL-negative group. These findings confirm the results of former investigations and underline the role of aCL in systemic lupus erythematosus.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Immunitat und Infektion

自引率

0.00%

发文量

期刊最新文献

[Antimicrobial oligopeptides--an important factor in non-specific defense against infection]. [Rational use of antimycotics against yeast infections]. [Leprosy--current aspects of a disease from biblical times]. [Actinomycetes canaliculitis--case reports]. [Gas gangrene as a manifestation of endogenous Clostridium septicum infection].