[ELISA和双扩散(DD5)试验对无症状人群包虫病诊断的评价]。

Revista de sanidad e higiene publica Pub Date : 1994-05-01
E Larrieu, C Dapcich, E Guarnera, E Coltorti, C Bianchi, A Moguilansky
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引用次数: 0

摘要

背景:通过免疫方法对人类包虫病进行早期诊断是阿根廷抗争计划(fight)在流行地区展示的最重要的活动之一,以提高对包虫病患者的预测。准确界定DD5和Elisa技术在无临床症状的人群中诊断包虫病的优势和局限性具有重要意义。方法:对Río Negro省某农村社区499名居民进行血清学分析,评价两种方法的敏感性、规范和预测价值。对eee和/或DD5血清学反应的居民进行US、RX和TC成像研究。根据其无反应性血清学选择对照组。与包虫病相容的病例直接进行手术。结果:DD5技术特异性为100%,敏感性仅为31%;另一方面,在8 DE的切割水平下,eee的规格为97%,灵敏度为63%。结论:强调美国作为第一影像学预后的价值是很重要的,而在目前的经验中,TC并没有显示大量的阳性图像,只能证实美国的发现。
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[Evaluation of ELISA and double diffusion (DD5) test in the diagnosis of human hydatidosis in asymptomatic population].

Background: The early diagnosis of Human Hydatidosis through immunologic methods has been one of the most important activities displayed by the Programme of Struggle (fight) in endemic areas of Argentina, to improve the prediction of the Hydatid patient. It is of great interest to define exactly the advantages and limitations of the DD5 and Elisa techniques in the diagnosis of hydatidosis in inhabited areas with no clinic symptoms of the disease.

Methods: For this, the sensibility, the specification and predictive value of both methods has been evaluated, studying serologically 499 inhabitants from a rural community in the Province of Río Negro. The inhabitants with reactive serology to EIE and/or DD5 are studied by means of images using US, RX and TC. A controlled group is selected according to its un-reactive serology. The cases compatible with Hydatidosis are directed to surgery.

Results: The DD5 technique is shown as 100% specific but with a sensibility of only 31%; on the other hand, EIE at a cutting level of 8 DE presents a specification of 97% with a sensibility of 63%.

Conclusions: It is important to underline the value of the US as the first image prognosis, while the TC, in the present experience, did not show a great number of positive images, allowing only to confirm the US findings.

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