动脉重建手术对重症腿部缺血预后的影响

M. Luther
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引用次数: 68

摘要

目的:分析在特定人群中积极血管重建政策对重症腿部缺血预后的影响。设计:回顾性调查研究区域22年来(1970-1991年)与人口数据相关的外科住院患者数据。地点:芬兰西部的瓦萨中心医院区。该地区设有一所中心医院和两所地区医院。资料:研究开始时的人群为16.5万人,研究结束时的人群为17.8万人,需要977例慢性重症腿部缺血(CLI)干预,397例急性缺血干预,313例非重症腿部缺血干预。主要观察指标:总截肢率和年龄组相关截肢率、死亡率、动脉介入率、肢体保留率。主要结果:人口;从1970年到1991年,65岁的人增加了50%。从1970年到1981年,主要截肢率增加了2.5倍。截肢的平均年龄从71岁增加到78岁,重建的平均年龄从68岁增加到74岁。自1980年以来,CLI的重建数量增加了100%,而从1983年到1991年,截肢率降低了60%。截肢后1年和5年生存率分别为55%和20%,重建后分别为83%和45%。重建后1年、3年和5年肢体保留率分别为83%、78%和77%,至死亡时肢体保留率为74%。结论:在CLI中,积极的重建政策可以在合理的死亡率和发病率的情况下降低截肢率,即使是在8、9岁的患者。
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The influence of arterial reconstructive surgery on the outcome of critical leg ischaemia

Objectives:

To analyse the effect of an aggressive vascular reconstruction policy on the outcome of critical leg ischaemia in a defined population.

Design:

A retrospective survey of surgical in-hospital patient data related to population data in the study region over 22 years (1970–1991).

Setting:

Vasa Central Hospital district in Western Finland. The area is served by one Central Hospital and two District Hospitals.

Materials:

The population of 165 000 at the beginning of the study and 178 000 at the end of the study needing 977 interventions for chronic critical leg ischaemia (CLI), 397 for acute ischaemia and 313 for noncritical leg ischaemia.

Chief outcome measures:

Total and age-group related major amputation rates, mortality, rates of arterial interventions, limb salvage rate.

Main results:

The population > 65 years of age increased by 50% from 1970 to 1991. Major amputation rates increased 2.5 times from 1970 to 1981. The mean age at amputation increased from 71 to 78 years and at reconstruction from 68 to 74 years. The increase in numbers of reconstructions for CLI by 100% from 1980 onwards was associated with a reduction in amputation rate by 60% from 1983 to 1991. The 1- and 5-year survival rate after amputation was 55 and 20% and after reconstruction 83 and 45%. After reconstruction 1-, 3- and 5-year limb salvage rates were 83, 78 and 77% and limb salvage until death was 74%.

Conclusions:

With an aggressive reconstruction policy in CLI it is possible to reduce amputation rates with a reasonable mortality and morbidity even in patients in the 8th and 9th decade of life.

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