动脉粥样硬化肠系膜动脉血运重建:90例连续患者的经验

Max Greve Christensen, Jorgen Ewald Lorentzen, Torben Veith Schroeder
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引用次数: 57

摘要

资料:女性54例,男性36例,年龄56岁(中位数;范围:34-78岁)进行了109次连续的肠系膜重建。90例初级手术的指征是25例非栓塞性急性肠系膜缺血,53例慢性缺血,12例与主动脉手术相关的预防性重建。肠系膜上动脉(SMA)重建术87例,腹腔轴或肝总动脉重建术6例。因此,只有3例患者进行了双侧区域血运重建。15例患者行血栓动脉内膜切除术,30例患者行SMA直接转位至肾下主动脉,48例患者行旁路手术。主要结局指标:累积无症状率和生存率。主要结果:围手术期(30 d)总死亡率为13%,主要原因是急性手术死亡率高达44%(11例),选择性手术死亡率为0%,预防性手术死亡率为8%。12例死亡中有9例是由于进展性肠系膜梗死。5年、10年和20年后的累计生存率分别为81%、60%和35%,这表明死亡率是年龄和性别匹配的丹麦人口的三倍。随访期间,30例患者症状复发,多见于急诊手术和SMA移位。结论:肠系膜血运重建术可产生持久的效果。然而,手术治疗急性缺血的死亡率很高,强调了早期手术的重要性。
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Revascularisation of atherosclerotic mesenteric arteries: Experience in 90 consecutive patients

Materials: 54 women and 36 men, aged 56 (median; range: 34–78 years) underwent 109 consecutive mesenteric reconstructions. The indication in 90 primary procedures was acute mesenteric ischaemia of non-embolic origin in 25 patients, chronic ischaemia in 53 and prophylactic reconstruction in connection with aortic surgery in 12 patients. The superior mesenteric artery (SMA) was revascularised in 87 patients and the coeliac axis or common hepatic artery in six. Thus, only three patients had both territories revascularised. Thromboendarterectomy was performed in 15 patients, transposition of the SMA directly into the infrarenal aorta in 30 and bypass in 48 patients. Chief outcome measures: Cumulative symptom-free and survival rates. Main results: The overall perioperative (30 days) mortality rate was 13%, mainly caused by the high mortality rate of 44% (11 patients) in the acutely operated, as the mortality was 0% in patients operated on electively and only one out of 12 patients (8%) died after a prophylactic operation. Nine of the twelve deaths were due to progressive mesenteric infarction. Cumulated survival rates were 81, 60 and 35% after 5, 10 and 20 years, respectively which indicated a mortality rate three times that of an age- and sex-matched Danish population. During follow-up symptoms recurred in 30 patients, more often following emergency surgery and SMA transposition. Conclusions: Mesenteric revascularisation may yield long lasting results. However, surgery for acute ischaemia carries a high mortality rate, emphasising the importance of early surgery.

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