与利福平相关的血清疾病样疾病。

Annals of allergy Pub Date : 1994-08-01

F M Parra, M J Pérez Elias, M Cuevas, A Ferreira

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引用次数: 0

摘要

我们描述了一个患有人类免疫缺陷病毒感染的病人，他在接受每日治疗剂量的结核药物治疗时出现了血清病反应的主要临床特征。观察到补体滴度降低以及循环免疫复合物显著水平的检测。利福平皮内试验6小时后皮肤试验结果为阳性。皮肤病变穿孔活检标本的直接免疫荧光未观察到免疫球蛋白或补体沉积。

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Serum sickness-like illness associated with rifampicin.

We describe a patient with human immunodeficiency virus infection who developed the main clinical features of a serum sickness reaction while receiving treatment with daily therapeutic doses of tuberculostatic drugs. A decrease in complement titers as well as a detection of significant levels of circulating immune complexes were observed. A positive skin test result was observed six hours after an intradermal test with rifampicin. No immunoglobulin or complement deposition was observed by direct immunofluorescence of a punch biopsy specimen from the cutaneous lesion.

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Annals of allergy

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