{"title":"纤维蛋白密封剂在骨诱导中的作用。","authors":"N Schwarz","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Mesenchymal cell stimulation and angiotropic effects suggest a fibrin sealant-mediated enhancement of osteogenesis. For its glueing capacity fibrin sealant is also regularly used in bone surgery. However, its influence on osteoregeneration is debatable. The effect of fibrin sealant on bone matrix gelatin dependent ectopic and orthotopic osteoinduction in rats was studied. Neither biochemical nor histologic parameters revealed a direct influence of fibrin sealant on any osteoinductive process.</p>","PeriodicalId":75497,"journal":{"name":"Annales chirurgiae et gynaecologiae. Supplementum","volume":"207 ","pages":"63-8"},"PeriodicalIF":0.0000,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The role of fibrin sealant in osteoinduction.\",\"authors\":\"N Schwarz\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Mesenchymal cell stimulation and angiotropic effects suggest a fibrin sealant-mediated enhancement of osteogenesis. For its glueing capacity fibrin sealant is also regularly used in bone surgery. However, its influence on osteoregeneration is debatable. The effect of fibrin sealant on bone matrix gelatin dependent ectopic and orthotopic osteoinduction in rats was studied. Neither biochemical nor histologic parameters revealed a direct influence of fibrin sealant on any osteoinductive process.</p>\",\"PeriodicalId\":75497,\"journal\":{\"name\":\"Annales chirurgiae et gynaecologiae. Supplementum\",\"volume\":\"207 \",\"pages\":\"63-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annales chirurgiae et gynaecologiae. Supplementum\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annales chirurgiae et gynaecologiae. Supplementum","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Mesenchymal cell stimulation and angiotropic effects suggest a fibrin sealant-mediated enhancement of osteogenesis. For its glueing capacity fibrin sealant is also regularly used in bone surgery. However, its influence on osteoregeneration is debatable. The effect of fibrin sealant on bone matrix gelatin dependent ectopic and orthotopic osteoinduction in rats was studied. Neither biochemical nor histologic parameters revealed a direct influence of fibrin sealant on any osteoinductive process.
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