{"title":"斜沸石型沸石对Wistar大鼠致癌性的研究。","authors":"E Tátrai, G Ungváry","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The long term carcinogenicity of clinoptilolite was examined in Wistar rats. Respirable clinoptilolite was given intratracheally in doses 0, 30, or 60 mg/animal to groups of 60 or 50 male and 50 female rats on one occasion. No significant dose-related increase was found in the incidence of tumours in any organ or tissue. The results indicated that clinoptilolite type zeolite had no carcinogenic activity in Wistar rats.</p>","PeriodicalId":20359,"journal":{"name":"Polish journal of occupational medicine and environmental health","volume":"6 1","pages":"27-34"},"PeriodicalIF":0.0000,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Study on carcinogenicity of clinoptilolite type zeolite in Wistar rats.\",\"authors\":\"E Tátrai, G Ungváry\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The long term carcinogenicity of clinoptilolite was examined in Wistar rats. Respirable clinoptilolite was given intratracheally in doses 0, 30, or 60 mg/animal to groups of 60 or 50 male and 50 female rats on one occasion. No significant dose-related increase was found in the incidence of tumours in any organ or tissue. The results indicated that clinoptilolite type zeolite had no carcinogenic activity in Wistar rats.</p>\",\"PeriodicalId\":20359,\"journal\":{\"name\":\"Polish journal of occupational medicine and environmental health\",\"volume\":\"6 1\",\"pages\":\"27-34\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polish journal of occupational medicine and environmental health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polish journal of occupational medicine and environmental health","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Study on carcinogenicity of clinoptilolite type zeolite in Wistar rats.
The long term carcinogenicity of clinoptilolite was examined in Wistar rats. Respirable clinoptilolite was given intratracheally in doses 0, 30, or 60 mg/animal to groups of 60 or 50 male and 50 female rats on one occasion. No significant dose-related increase was found in the incidence of tumours in any organ or tissue. The results indicated that clinoptilolite type zeolite had no carcinogenic activity in Wistar rats.
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