在接受去铁胺治疗或不接受去铁胺治疗的重度和中度-地中海贫血患者中,眼部受累与年龄相关。

M Rinaldi, M Della Corte, V Ruocco, C D'Onofrio, G Zanotta, A Romano
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引用次数: 0

摘要

我们检查了25例库利病患者和5例中β -地中海贫血患者。平均年龄15±6.3岁。15例患者(18岁或以上),其中3例患有中-地中海贫血,出现眼部异常。因此不可能在实验室数据和眼部损伤之间建立关联;他们对未经治疗的-地中海贫血受试者的观察表明,眼部异常不能仅仅归因于去铁胺治疗。
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Ocular involvement correlated with age in patients affected by major and intermedia beta-thalassemia treated or not with desferrioxamine.

We examined 25 patients affected from Cooley's disease and five by beta-thalassemia intermedia. The mean age was 15 +/- 6.3 years. Fifteen patients, (18 years or older) three of them affected by beta-thalassemia intermedia, presented ocular abnormalities. So it was impossible to establish a correlation between laboratory data and ocular damages; their observation, with reference to untreated beta-thalassemia subjects, suggested that ocular abnormalities cannot be only attributed to desferrioxamine treatment.

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