{"title":"硒替代在炎性疾病中的作用机制。急性胰腺炎患者抗氧化酶活性的改变[j]。","authors":"U Zelck, U Karnstedt","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>From 20 patients with acute pancreatitis the activities of the antioxidative enzymes glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) were estimated in the blood serum immediately before and during therapy with sodium selenite. The results demonstrate significant (p < 0.01 respectively < 0.05) enhanced activities of GSH-Px under the selenite therapy. Serum SOD activities were not significant influenced by the selenium treatment. The results obtained were not dependent on the reference basis (units/mg protein or U/l serum) used.</p>","PeriodicalId":23901,"journal":{"name":"Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete","volume":"48 2","pages":"78-81"},"PeriodicalIF":0.0000,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The mechanism of action of selenium substitution in inflammatory diseases. Modification of the activity of antioxidative enzymes in patients with acute pancreatitis].\",\"authors\":\"U Zelck, U Karnstedt\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>From 20 patients with acute pancreatitis the activities of the antioxidative enzymes glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) were estimated in the blood serum immediately before and during therapy with sodium selenite. The results demonstrate significant (p < 0.01 respectively < 0.05) enhanced activities of GSH-Px under the selenite therapy. Serum SOD activities were not significant influenced by the selenium treatment. The results obtained were not dependent on the reference basis (units/mg protein or U/l serum) used.</p>\",\"PeriodicalId\":23901,\"journal\":{\"name\":\"Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete\",\"volume\":\"48 2\",\"pages\":\"78-81\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
对20例急性胰腺炎患者在亚硒酸钠治疗前后血清抗氧化酶谷胱甘肽过氧化物酶(GSH-Px)和超氧化物歧化酶(SOD)的活性进行了测定。结果表明，亚硒酸盐处理显著(p < 0.01, p < 0.05)提高了GSH-Px活性。硒处理对血清SOD活性无显著影响。所获得的结果不依赖于所使用的参考基础(单位/毫克蛋白质或U/l血清)。
[The mechanism of action of selenium substitution in inflammatory diseases. Modification of the activity of antioxidative enzymes in patients with acute pancreatitis].
From 20 patients with acute pancreatitis the activities of the antioxidative enzymes glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) were estimated in the blood serum immediately before and during therapy with sodium selenite. The results demonstrate significant (p < 0.01 respectively < 0.05) enhanced activities of GSH-Px under the selenite therapy. Serum SOD activities were not significant influenced by the selenium treatment. The results obtained were not dependent on the reference basis (units/mg protein or U/l serum) used.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
