在重金属预处理的HeLa细胞中,硝酸处理的腺病毒增强的再激活与增强的诱变无关

S.M. Piperakis
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引用次数: 0

摘要

研究了一种腺病毒2型温度敏感生长突变体在感染对照组后,经不同剂量的硝酸处理后频率的逆转。紫外线照射下,氯化镉和氯化锌处理HeLa细胞。未观察到突变增强。
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Enhanced reactivation of nitrous acid treated adenovirus is not associated with enhanced mutagenesis in pretreated with heavy metals HeLa cells

The reversion of frequency of an adenovirus 2 temperature-sensitive growth mutant treated with different doses of nitrous acid was determined after infection of control. UV-irradiated, cadmium chloride and zinc chloride treated HeLa cells. No enhanced mutagenesis was observed.

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