[预止痛与聚乙二醇正位灌肠对结直肠癌术后肠梗阻持续时间的影响]。

K Gründel, W Schwenk, B Böhm, J M Müller
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引用次数: 1

摘要

在一项前瞻性随机研究中,100例接受常规(n = 66)或腹腔镜(n = 34)结肠直肠癌切除术的患者,用2升聚乙二醇(PEG)溶液(a组,n = 50)联合泻药进行机械灌洗,与单独用4升聚乙二醇(PEG)灌洗(B组,n = 50)进行比较。探讨肠道准备对术后肠梗阻的影响。肠准备的效果由一名不知道准备类型的外科医生在术中确定。记录手术结束至第一次放屁或排便的时间间隔。两组间制剂疗效无显著差异(A组:94%,B组:84%;P = 0.5)。首次放屁间隔时间(A: 3.1 +/- 1.2天,B: 3.2 +/- 1.3天;P = 0.6)或排便(A: 3.9 +/- 1.3天,B: 4.1 +/- 1.3天;P = 0.5)组间差异无统计学意义。在多变量分析(年龄、性别、手术、手术时间和手术类型、肠道准备)中发现的唯一延长术后肠梗阻持续时间的因素是手术类型。常规手术后第一次排便发生在3.2 +/- 1.1天,腹腔镜手术后第一次排便发生在4.3 +/- 1.2天(P < 0.001)。术前肠道准备的类型对术后肠梗阻的持续时间没有影响。腹腔镜手术后第一次排便前的时间间隔较短。
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[Effect of orthograde intestinal irrigation with Prepacol and polyethyleneglycol solution on duration of postoperative ileus after colorectal resections].

In a prospective randomized study in 100 patients undergoing conventional (n = 66) or laparoscopic (n = 34) colorectal resection, mechanical lavage with 2 l of a polyethylene glycol (PEG) solution (group A, n = 50) combined with a laxative was compared with lavage with 4 l of PEG alone (group B, n = 50). The influence of bowel preparation on postoperative ileus was investigated. The efficacy of bowel preparation was determined intraoperatively by a surgeon blind to the type of preparation. The time interval between the end of the operation an first flatus or bowel movement was recorded. The efficacy of preparation was no different between the groups (group A: 94%, group B: 84%; P = 0.5). The time lapse before first flatus (A: 3.1 +/- 1.2 days, B: 3.2 +/- 1.3 days; P = 0.6) or bowel movement (A: 3.9 +/- 1.3 days, B: 4.1 +/- 1.3 days; P = 0.5) also did not differ between the groups. The only factor found in multivariate analysis (age, sex, operation, duration and type of surgery, bowel preparation) to prolong the duration of postoperative ileus was the type of surgery. The first bowel movement occurred 3.2 +/- 1.1 days after conventional surgery and 4.3 +/- 1.2 days (P < 0.001) after laparoscopic surgery. The type of preoperative bowel preparation had no influence on the duration of postoperative ileus. The postoperative interval before the first bowel movement was shorter after laparoscopic surgery.

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