{"title":"稳定表达腮腺炎病毒糖蛋白的细胞系的建立。","authors":"M Hishiyama, K Tanabayashi, K Takeuchi, A Yamada","doi":"10.7883/yoken1952.49.29","DOIUrl":null,"url":null,"abstract":"<p><p>We established two cell lines that stably express hemagglutinin-neuraminidase (HeLa-HN) and fusion proteins (HeLa-F) of a fusogenic strain of mumps virus. Infection of HeLa-F cells with a nonfusogenic strain resulted in induction of extensive cell fusion. On the other hand, HeLa-HN cells appeared resistant to cell fusion induced by mumps virus infection.</p>","PeriodicalId":14531,"journal":{"name":"Japanese journal of medical science & biology","volume":"49 1","pages":"29-38"},"PeriodicalIF":0.0000,"publicationDate":"1996-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Establishment of cell lines stably expressing mumps virus glycoproteins.\",\"authors\":\"M Hishiyama, K Tanabayashi, K Takeuchi, A Yamada\",\"doi\":\"10.7883/yoken1952.49.29\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We established two cell lines that stably express hemagglutinin-neuraminidase (HeLa-HN) and fusion proteins (HeLa-F) of a fusogenic strain of mumps virus. Infection of HeLa-F cells with a nonfusogenic strain resulted in induction of extensive cell fusion. On the other hand, HeLa-HN cells appeared resistant to cell fusion induced by mumps virus infection.</p>\",\"PeriodicalId\":14531,\"journal\":{\"name\":\"Japanese journal of medical science & biology\",\"volume\":\"49 1\",\"pages\":\"29-38\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1996-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Japanese journal of medical science & biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7883/yoken1952.49.29\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese journal of medical science & biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7883/yoken1952.49.29","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Establishment of cell lines stably expressing mumps virus glycoproteins.
We established two cell lines that stably express hemagglutinin-neuraminidase (HeLa-HN) and fusion proteins (HeLa-F) of a fusogenic strain of mumps virus. Infection of HeLa-F cells with a nonfusogenic strain resulted in induction of extensive cell fusion. On the other hand, HeLa-HN cells appeared resistant to cell fusion induced by mumps virus infection.