土耳其接触石棉居民姊妹染色单体交换频率

Hamiyet Dönmez , Yusuf özkul , Ramazan Uçak
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引用次数: 12

摘要

在土耳其伊夫里兹-扎纳帕山谷村庄的居民中观察到胸膜间皮瘤、肺癌、胸膜钙化和纤维化。早先的报告指出,这些地方性的病理状况是由于吸入放线石石棉引起的,放线石石棉是一种通常不加区别地用于粉刷房屋墙壁和地板的矿物。本研究对Ivriz-Zanapa山谷Yassikaya村的40名居民和20名对照者进行了进一步调查。培养外周血淋巴细胞,72h后收获姊妹染色单体交换(SCE)频率。与对照人群相比,居民的平均SCE率升高。
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Sister chromatid exchange frequency in inhabitants exposed to asbestos in Turkey

Pleural mesothelioma, lung cancer, pleural calcification and fibrosis have been observed among inhabitants of the villages in Ivriz-Zanapa valley in Turkey. Earlier reports have stated that these endemic pathological conditions are caused by the inhalation of actinolite asbestos, a mineral commonly used indiscriminately to paint the walls and floors of houses. In the present study, 40 inhabitants in Yassikaya village in Ivriz-Zanapa valley and 20 controls were further investigated. The peripheral blood lymphocytes were cultured and harvested at 72 h for sister chromatid exchange (SCE) frequency. Inhabitants had a raised mean SCE rate compared with a control population.

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