香港华人急性淋巴细胞白血病患者异常大小c-kit转录本的表达。

Clinical and laboratory haematology Pub Date : 1996-12-01

C H Chui, F Y Lau, A H Chan, J C Tang, C H Hui, C C Lam, L C Chan, G Cheng

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摘要

大多数急性髓性白血病(AML)患者的母细胞表达c-kit mRNA。然而，在急性淋巴细胞白血病(ALL)和淋巴细胞增生性疾病患者中未观察到c-kit表达。我们在此报告了在两名患有前b型ALL和普通ALL的中国香港患者中检测到异常大小的c-kit mRNA。

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Expression of an abnormal sized c-kit transcript in Hong Kong Chinese acute lymphoblastic leukaemia patients.

Blast cells from a majority of acute myelogenous leukaemia (AML) patients express c-kit mRNA. However, c-kit expression has not been observed in patients with acute lymphoblastic leukaemia (ALL) and lymphoproliferative disease. We report here the detection of an abnormal sized c-kit mRNA in two Hong Kong Chinese patients with pre-B ALL and common ALL.

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Clinical and laboratory haematology

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