{"title":"使用体细胞杂交面板的遗传标记的区域分配:猪基因组可用的WWW交互程序。","authors":"C Chevalet, J Gouzy, M SanCristobal-Gaudy","doi":"10.1093/bioinformatics/13.1.69","DOIUrl":null,"url":null,"abstract":"<p><strong>Motivation: </strong>Quick and easy gene mapping by the use of a panel of cytogenetically characterized somatic cell hybrids is possible, even if some discordant experimental results arise.</p><p><strong>Results: </strong>An interactive program is proposed and is made available on a WWW site to users of a somatic cell hybrid panel. Assignments to chromosomes and subchromosomal regions are based on likelihood calculations and Bayes' theorem, and a confidence level is provided. The method is illustrated in the case of the pig genome.</p>","PeriodicalId":77081,"journal":{"name":"Computer applications in the biosciences : CABIOS","volume":"13 1","pages":"69-73"},"PeriodicalIF":0.0000,"publicationDate":"1997-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/bioinformatics/13.1.69","citationCount":"65","resultStr":"{\"title\":\"Regional assignment of genetic markers using a somatic cell hybrid panel: a WWW interactive program available for the pig genome.\",\"authors\":\"C Chevalet, J Gouzy, M SanCristobal-Gaudy\",\"doi\":\"10.1093/bioinformatics/13.1.69\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Motivation: </strong>Quick and easy gene mapping by the use of a panel of cytogenetically characterized somatic cell hybrids is possible, even if some discordant experimental results arise.</p><p><strong>Results: </strong>An interactive program is proposed and is made available on a WWW site to users of a somatic cell hybrid panel. Assignments to chromosomes and subchromosomal regions are based on likelihood calculations and Bayes' theorem, and a confidence level is provided. The method is illustrated in the case of the pig genome.</p>\",\"PeriodicalId\":77081,\"journal\":{\"name\":\"Computer applications in the biosciences : CABIOS\",\"volume\":\"13 1\",\"pages\":\"69-73\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1997-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1093/bioinformatics/13.1.69\",\"citationCount\":\"65\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computer applications in the biosciences : CABIOS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/bioinformatics/13.1.69\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computer applications in the biosciences : CABIOS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/bioinformatics/13.1.69","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Regional assignment of genetic markers using a somatic cell hybrid panel: a WWW interactive program available for the pig genome.
Motivation: Quick and easy gene mapping by the use of a panel of cytogenetically characterized somatic cell hybrids is possible, even if some discordant experimental results arise.
Results: An interactive program is proposed and is made available on a WWW site to users of a somatic cell hybrid panel. Assignments to chromosomes and subchromosomal regions are based on likelihood calculations and Bayes' theorem, and a confidence level is provided. The method is illustrated in the case of the pig genome.