食管癌胃管重建术后颈吻合口狭窄。对患者样本的评估[1989-1995]。

Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01
C J Bruns, M Gawenda, B Wolfgarten, M Walter
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引用次数: 0

摘要

食管癌食管切除术胃管重建术后常见的晚期并发症是颈部吻合口出现症状性良性纤维化狭窄,需要扩张。由于食管癌的预后仍然较差,吞咽困难等不良的功能结果影响生活质量。在一项回顾性分析中,我们对食管切除术和胃管重建后颈部吻合口狭窄的潜在影响进行了评估。自1989年1月1日至1995年7月31日,我院共收治食管癌173例。133例患者行经食道解剖;40例患者行经胸整体切除。30天死亡率为7.5%(13例)。术后6-12周,36.4%(63例)发生颈吻合口纤维化狭窄,需要扩张。97例患者未发生吻合口纤维化狭窄。两组吻合口瘘的发生率有显著差异:63例颈吻合口纤维化狭窄患者中有23.8%在吻合口瘘发生之前发生吻合口瘘(P < 0.001),而97例颈吻合口愈合正常的患者中没有发生吻合口瘘。此外,63例颈吻合口纤维化狭窄患者中既往存在糖尿病的患者(37.5%,n = 23)明显多于97例无吻合口狭窄的患者(P < 0.01)。
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[Cervical anastomotic stenosis after gastric tube reconstruction in esophageal carcinoma. Evaluation of a patient sample 1989-1995].

Common late complications after esophagectomy and gastric tube reconstruction for esophageal carcinoma are symptomatic, benign fibrotic stenoses of the cervical anastomosis, which require dilatation. Since the prognosis of esophageal carcinoma still remains poor, bad functional results such as dysphagia affect quality of life. In a retrospective analysis, our patients were evaluated with regard to the underlying effects of cervical anastomotic stenosis after esophagectomy and gastric tube reconstruction. From 1 January 1989 to 31 July 1995, 173 patients with carcinoma of the esophagus were operated in our institution. Transhiatal esophageal dissection was performed in 133 patients; 40 patients underwent transthoracic en bloc resection. The 30-day mortality rate was 7.5% (13 patients). Postoperative fibrotic stenosis of the cervical anastomosis requiring dilatation occurred in 36.4% (63 patients) 6-12 weeks after operation. Fibrotic stenosis of the cervical anastomosis did not develop in 97 patients. There was a significant difference concerning the incidence of anastomotic leaks within both groups: whereas in 23.8% of the 63 patients who developed a fibrotic stricture of the cervical anastomosis an anastomotic leak preceded this event (P < 0.001), no anastomotic leak occurred in the group of 97 patients with normal healing of the cervical anastomosis. In addition, significantly (P < 0.01) more patients (37.5%, n = 23) with preexisting diabetes mellitus could be found among the 63 patients who developed a fibrotic stricture of the cervical anastomosis, in contrast to the 97 patients without anastomotic stenosis.

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