核磁共振在结构生物学中的应用。

Nature Structural Biology Pub Date : 1997-10-01

G Wagner

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引用次数: 0

摘要

核磁共振波谱(NMR)由于能够在半生理条件下确定生物大分子的原子分辨率结构，已成为结构生物学研究的重要工具。核磁共振为研究关键的生物现象提供了一种手段，包括蛋白质结构、动力学和折叠，以及药物设计的实用方法。

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An account of NMR in structural biology.

With the ability to determine atomic resolution structures of biological macromolecules in semi-physiological conditions, nuclear magnetic resonance spectroscopy (NMR) has become an eminent tool in structural biology. NMR provides a means for studying critical biological phenomena including protein structure, dynamics and folding as well as a practical approach to drug design.

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Nature Structural Biology

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