在生殖器疱疹诊断中患者对类型特异性血清学试验的态度。

I Fairley, E F Monteiro
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引用次数: 45

摘要

目的:了解患者对2型单纯疱疹病毒(HSV-2)血清检测的态度,以及提供有关生殖器疱疹、血液检测的详细信息的效果及其意义。方法:要求连续的泌尿生殖医学门诊就诊人员完成一份匿名自我填写的问卷。一半的人得到了最少的额外信息,而另一半人得到了详细的信息表。结果:总体而言,200名中位年龄为27岁(15-57岁)的门诊就诊人员完成了问卷调查,92.4%的人想知道自己是否感染了生殖器疱疹,90.8%的人想知道他们的伴侣是否感染了生殖器疱疹;65%的人认为检测是筛查的一部分,无需进一步讨论。总的来说,在1-10的范围内,2%的人打了1分(相当于绝对不想考试),而45.5%的人打了10分(相当于绝对想考试)。总体中位数得分为9(95%置信区间为8-10),表明强烈支持测试。与一般愿望相比,在五种描述的假设情况中进行测试的愿望显著增加(p < 0.001)。结论:诊所参与者表示强烈倾向于接受2型单纯疱疹病毒的血清检测,这一点并未因提供强调含义的信息而改变,尽管受到询问他们的背景的显著影响。如果能够提供可靠的检测,需求水平可能对实验室和咨询资源产生重要影响。
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Patient attitudes to type specific serological tests in the diagnosis of genital herpes.

Objective: To assess patient attitudes to HSV-2 serotesting and the effect of providing detailed information regarding genital herpes, the blood test, and its implications.

Methods: Consecutive genitourinary medicine clinic attenders were asked to complete an anonymous self administered questionnaire. Half received minimal additional information while the other half received a detailed information sheet.

Results: Overall, 200 clinic attenders with a median age of 27 years (range 15-57) completed the questionnaire, 92.4% wanted to know if they, and 90.8% if their partners, had been infected with genital herpes; 65% expected testing as part of screening without further discussion. Overall, on a scale of 1-10, 2% scored 1 (equivalent to definitely not wanting a test), while 45.5% scored 10 (equivalent to definitely wanting a test). The overall median score was 9 (95% confidence interval 8-10) suggesting a strong opinion in favour of testing. The desire to test in each of five described hypothetical situations increased significantly (p < 0.001) when compared with the general desire.

Conclusions: Clinic attenders expressed a strong preference to be serotested for HSV-2 which was unaltered by the provision of information highlighting implications, although influenced significantly by the context in which they were asked. Should reliable tests become available the level of demand could have important implications on laboratory and counselling resources.

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