老年人血液透析的充分性。

R M Lindsay, E Spanner
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引用次数: 9

摘要

尽管技术有所进步,但无论年龄大小,透析的死亡率和发病率仍然很高。虽然其中一些是可以解释和接受的,并与心脏病、恶性肿瘤、糖尿病等合并症有关,但也有许多是可以预防的。来自文献的数据表明,提供足够的透析(以Kt/V(尿素)> 1.2或尿素还原率(URR) > 65%来确定)将改善预后。注意患者的营养状况也要有影响。血清尿素、肌酐、白蛋白、阴离子间隙水平低、理想体重和饮食蛋白质摄入量低(蛋白质分解代谢率降低)是不良预后特征。老年人更有可能拥有这些特征。虽然许多因素可能导致蛋白质营养不良,但透析不足应该是一个容易识别和可逆的原因。透析不足将不可避免地导致营养不良,并对预后产生不利影响。
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Adequacy of haemodialysis in the elderly.

Mortality and morbidity on dialysis remains high regardless of age in spite of technological improvements. While some of this is explainable and acceptable and related to co-morbid problems such as heart disease, malignancy, diabetes, etc. much is also preventable. Data from the literature would indicate that the provision of adequate dialysis as determined by a Kt/V (urea) of > 1.2 or a urea reduction rate (URR) > 65% will improve outcome. Attention to the nutritional status of the patient should also have impact. Low serum levels of urea, creatinine, albumin, anion gap, ideal body weight, and a low dietary protein intake as suggested by a reduced protein catabolic rate, are bad prognostic features. The elderly are more likely to have these features. While many factors may contribute to or cause protein malnutrition, underdialysis should be one easily recognized and reversible cause. Underdialysis will inevitably lead to poor nutrition and have an adverse effect on outcome.

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