【原发性血管源性肠梗死的致命结局因素】。

Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01
M Gawenda, P Scherwitz, M Walter, H Erasmi
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引用次数: 0

摘要

尽管诊断和治疗的进步,肠系膜血管闭塞与肠梗死往往是致命的。决定高死亡率的参数在文献中很少讨论。通过单变量统计分析,我们将患者的治疗结果与20个参数相关联。在1984年1月1日至1996年4月30日期间,我们治疗了22名男性和18名女性血管源性急性肠缺血。所有患者均行剖腹手术,其中40% (n = 16)因诊断为肠系膜梗死。15% (n = 6)的剖腹探查;34例(85%)行肠切除术。所有患者的死亡率为55% (n = 22)。对20个参数的单因素分析显示,治疗结果与既往糖尿病、住院时间和高ASA等级显著相关。与切除肠的长度无关。大多数决定肠梗死死亡率的参数都是预先存在的,不能受到影响,但如果在几乎完全的小肠梗死一侧进行根治性和积极的切除,然后进行选择性的二次手术,一些患者可以获得生存。即使是短肠综合症也可以治疗。患者可以在家中通过肠外营养恢复到接近正常的生活方式,并获得可接受的生活质量。
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[Fatal outcome factors of intestinal infarct of primary vascular origin].

Despite diagnostic and therapeutic advances, mesenteric vascular occlusion with intestinal infarction is often fatal. Parameters determining the high mortality are seldom discussed in the literature. By univariate statistical analysis we correlated the therapeutic outcome of our patients to 20 parameters. Between 1 January 1984 and 30 April 1996 we treated 22 men and 18 women with acute bowel ischemia of vascular origin. All patients underwent laparotomy, 40% (n = 16) due to the diagnosis of mesenteric infarction. In 15% (n = 6) the laparotomy was only exploratory; in 34 cases (85%) bowel resection was carried out. Mortality for all patients was 55% (n = 22). Univariate analysis of the 20 parameters showed that the therapeutic outcome was significantly correlated to a pre-existing diabetes, the course of hospitalization, and the high ASA class. There was no correlation to the length of resected bowel. Most parameters that determine the mortality of bowel infarction are pre-existing and cannot be influenced, but survival can be achieved in some patients if radical and aggressive resection is carried out at the side of almost complete small bowel infarction and followed by an elective second-look operation. Even short-bowel syndrome can be treated. Patients can return to a near normal lifestyle with an acceptable quality of life with the aid of parenteral nutrition at home.

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