H. Ahissou , T. Lebreton de Vonne , F. Esnard , H. Mouray
{"title":"草畜(Thryonomys swinderianus)炎症标志物的进化:与兔(Oryctolagus cuuniculus)和大鼠(Rattus norvegicus)的比较","authors":"H. Ahissou , T. Lebreton de Vonne , F. Esnard , H. Mouray","doi":"10.1016/S0300-9629(97)00244-2","DOIUrl":null,"url":null,"abstract":"<div><p>An inflammatory reaction was induced in grass-cutters (<em>Thryonomys swinderianus</em>) by injecting turpentine. The changes in the plasma haptoglobin, fibrinogen, <em>α</em><sub>2</sub> macroglobulin and immunoglobulin G was followed for 23 days by immunonephelometry. The results were compared to rat and rabbit. The showed that (a) the inflammatory reaction is delayed in the grass-cutter compared to rats and rabbits; (b) the concentration of haptoglobin increases less than in rat and rabbit; (c) the fibrinogen concentration is very low in the grass-cutter, despite hypercoagulability of blood; (d) the changes in the plasma <em>α</em><sub>2</sub>-macroglobulin in the grass-cutter seems to be comparable to that of rabbit <em>α</em><sub>1</sub> macroglobulin in amplitude and in its slow return to the initial concentration; and (e) fibrinogen and haptoglobin are suitable markers for grass-cutter inflammation monitoring.</p></div>","PeriodicalId":10612,"journal":{"name":"Comparative Biochemistry and Physiology Part A: Physiology","volume":"118 4","pages":"Pages 1309-1312"},"PeriodicalIF":0.0000,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0300-9629(97)00244-2","citationCount":"0","resultStr":"{\"title\":\"Evolution of grass-cutter (Thryonomys swinderianus) inflammation markers: Comparison with rabbit (Oryctolagus cuniculus) and rat (Rattus norvegicus)\",\"authors\":\"H. Ahissou , T. Lebreton de Vonne , F. Esnard , H. Mouray\",\"doi\":\"10.1016/S0300-9629(97)00244-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>An inflammatory reaction was induced in grass-cutters (<em>Thryonomys swinderianus</em>) by injecting turpentine. The changes in the plasma haptoglobin, fibrinogen, <em>α</em><sub>2</sub> macroglobulin and immunoglobulin G was followed for 23 days by immunonephelometry. The results were compared to rat and rabbit. The showed that (a) the inflammatory reaction is delayed in the grass-cutter compared to rats and rabbits; (b) the concentration of haptoglobin increases less than in rat and rabbit; (c) the fibrinogen concentration is very low in the grass-cutter, despite hypercoagulability of blood; (d) the changes in the plasma <em>α</em><sub>2</sub>-macroglobulin in the grass-cutter seems to be comparable to that of rabbit <em>α</em><sub>1</sub> macroglobulin in amplitude and in its slow return to the initial concentration; and (e) fibrinogen and haptoglobin are suitable markers for grass-cutter inflammation monitoring.</p></div>\",\"PeriodicalId\":10612,\"journal\":{\"name\":\"Comparative Biochemistry and Physiology Part A: Physiology\",\"volume\":\"118 4\",\"pages\":\"Pages 1309-1312\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1997-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0300-9629(97)00244-2\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Comparative Biochemistry and Physiology Part A: Physiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0300962997002442\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comparative Biochemistry and Physiology Part A: Physiology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0300962997002442","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Evolution of grass-cutter (Thryonomys swinderianus) inflammation markers: Comparison with rabbit (Oryctolagus cuniculus) and rat (Rattus norvegicus)
An inflammatory reaction was induced in grass-cutters (Thryonomys swinderianus) by injecting turpentine. The changes in the plasma haptoglobin, fibrinogen, α2 macroglobulin and immunoglobulin G was followed for 23 days by immunonephelometry. The results were compared to rat and rabbit. The showed that (a) the inflammatory reaction is delayed in the grass-cutter compared to rats and rabbits; (b) the concentration of haptoglobin increases less than in rat and rabbit; (c) the fibrinogen concentration is very low in the grass-cutter, despite hypercoagulability of blood; (d) the changes in the plasma α2-macroglobulin in the grass-cutter seems to be comparable to that of rabbit α1 macroglobulin in amplitude and in its slow return to the initial concentration; and (e) fibrinogen and haptoglobin are suitable markers for grass-cutter inflammation monitoring.