良性术后胆管狭窄

Keith D. Lillemoe MD (Professor of Surgery)
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引用次数: 56

摘要

绝大多数术后胆管狭窄发生在胆囊切除术后,自从引入腹腔镜胆囊切除术以来,这些损伤的发生率增加了。胆管损伤通常在术后早期出现,梗阻性黄疸或胆漏是最常见的表现形式。在术后出现胆管狭窄的患者中,胆管炎是最常见的症状。诊断胆管狭窄的“金标准”是胆管造影。经皮经肝胆道造影通常比内窥镜逆行胆道造影更有价值,因为它确定了近端胆道树的解剖结构,用于外科重建。Roux-en-Y肝空肠吻合术是治疗胆管狭窄最常用的手术方法,总体效果最好。胆管狭窄的手术修复效果良好,大多数系列的长期成功率超过80%。最近的数据表明,在大约3年的中期随访中,腹腔镜胆囊切除术后胆管损伤修复可以获得良好的结果。经皮和内窥镜技术扩张胆管狭窄可以有效地辅助管理胆管狭窄,如果解剖情况和临床情况支持这种方法。在选定的患者中,内镜和经皮扩张的结果与手术重建的结果相当。
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Benign post-operative bile duct strictures

The vast majority of post-operative bile duct strictures occur following cholecystectomy, these injuries having been seen at an increased frequency since the introduction of laparoscopic cholecystectomy. Bile duct injuries usually present early in the post-operative period, obstructive jaundice or evidence of a bile leak being the most common mode of presentation. In patients presenting with a post-operative bile duct stricture months to years after surgery, cholangitis is the most common symptom. The ‘gold standard’ for the diagnosis of bile duct strictures is cholangiography. Percutaneous transhepatic cholangiography is generally more valuable than endoscopic retrograde cholangiography in that it defines the anatomy of the proximal biliary tree that is to be used in surgical reconstruction. The most commonly employed surgical procedure with the best overall results for the treatment of bile duct stricture is a Roux-en-Y hepaticojejunostomy. The results of the surgical repair of bile duct strictures are excellent, long-term success rates being in excess of 80% in most series. Recent data have suggested that, at intermediate follow-up of approximately 3 years, an excellent outcome can be obtained following repair of bile duct injuries after laparoscopic cholecystectomy. Percutaneous and endoscopic techniques for the dilatation of bile duct strictures can be useful adjuncts to the management of bile duct strictures if the anatomical situation and clinical scenario favour this approach. In selected patients, the results of both endoscopic and percutaneous dilatation are comparable to those of surgical reconstruction.

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