R Nisell, S Arnér, A Ekblom, P Hansson, T Lundeberg, G Németh, I Petersson
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引用次数: 0
摘要
这篇文章是1996年瑞典医学协会年会上举行的风湿痛专题讨论会的综合报告。讨论了风湿性疾病疼痛的各个方面,如生理、神经体液和神经源性机制、感觉刺激治疗、机械性和炎症性疼痛的区分、通过改善初级和三级保健机构之间的合作来提高质量、使用(中枢和外周作用的)阿片类药物、选择性环加氧酶抑制剂和NMDA (n -甲基- d -天冬氨酸)受体拮抗剂进行药物治疗。对于因疼痛问题而加重的风湿病患者,与其他患者一样,疼痛诊断是至关重要的。这可以通过分析导致疼痛的原因和程度以及疼痛行为的社会、心理、生理和医学因素,以及疼痛可能是伤害性的程度(即炎症性、机械性或缺血性)、神经源性或特发性的程度来实现。疼痛分析之后应该针对患者最关键的问题进行个体化治疗,从而提高最佳治疗结果的前景。
[Pain analysis is vital in rheumatic diseases. Pain often causes much worry to patients].
The article consists of a synthesis of a rheumatic pain symposium held at the annual meeting of the Swedish Medical Association in 1996. Various aspects of pain in rheumatic diseases were discussed, such as physiological, neurohumoral and neurogenic mechanisms, sensory stimulation treatment, differentiation of mechanical and inflammatory pain, quality enhancement by improved co-operation between primary and tertiary care facilities, pharmacological treatment with (centrally and peripherally acting) opioids, selective cyclo-oxygenase inhibitors, and NMDA (N-methyl-D-aspartate) receptor antagonists. For patients with rheumatic disorders exacerbated by pain problems, as for other patients, a pain diagnosis is of fundamental importance. This can be achieved by analysis of the social, psychological, physiological and medical factors contributing to the cause and degree of pain and to pain behaviour, and of the extent to which the pain may be nociceptive (i.e., inflammatory, mechanical, or ischaemic in origin), neurogenic or idiopathic. Pain analysis should be followed by individualised treatment focused on the patient's most crucial problems, thus enhancing the prospect of optimal treatment outcome.